The paper reviewed the origin of the chakra system on a more scientific basis. We have studied the history of the seven chakra system and Amit Ray’s 114 chakra system. A couple of decades ago, it was believed that the seven chakras are worth only for spiritual development. However, recent scientific studies have proven the opposite, uncovering several regulatory chakras in the human body are deeply related to human psychology. Scientists observed several regulatory micro-networks in the human body, deeply connected with immunity, health, mental peace, emotions and happiness. Biological models of behavior have become increasingly prominent in psychological theory, particularly with the development of various neuro-imaging tools. The field of neuropsychology, which studies the brain and the connected nervous system, is growingly feeling the role chakras in human psychology. In this paper, we tried to trace the history of the chakra system on a more scientific basis.